Cargando…
The Antagonist pGlu-βGlu-Pro-NH(2) Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor
After we identified pGlu-βGlu-Pro-NH(2) as the first functional antagonist of the cholinergic central actions of the thyrotropin-releasing hormone (TRH, pGlu-His-Pro-NH(2)), we became interested in finding the receptor-associated mechanism responsible for this antagonism. By utilizing a human TRH re...
Autores principales: | De La Cruz, Daniel L., Prokai, Laszlo, Prokai-Tatrai, Katalin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433856/ https://www.ncbi.nlm.nih.gov/pubmed/34500828 http://dx.doi.org/10.3390/molecules26175397 |
Ejemplares similares
-
[β-Glu(2)]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2021) -
Prodrugs of Thyrotropin-Releasing Hormone and Related Peptides as Central Nervous System Agents
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2009) -
Design and Exploratory Neuropharmacological Evaluation of Novel Thyrotropin-Releasing Hormone Analogs and Their Brain-Targeting Bioprecursor Prodrugs
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2013) -
Brain Delivery of Thyrotropin-Releasing Hormone via a Novel Prodrug Approach
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019) -
A Novel Prodrug Approach for Central Nervous System-Selective Estrogen Therapy
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2019)