Structural Insights and Docking Analysis of Adamantane-Linked 1,2,4-Triazole Derivatives as Potential 11β-HSD1 Inhibitors

The solid-state structural analysis and docking studies of three adamantane-linked 1,2,4-triazole derivatives are presented. Crystal structure analyses revealed that compound 2 crystallizes in the triclinic P-1 space group, while compounds 1 and 3 crystallize in the same monoclinic P2(1)/c space gro...

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Detalles Bibliográficos
Autores principales: Osman, Doaa A., Macías, Mario A., Al-Wahaibi, Lamya H., Al-Shaalan, Nora H., Zondagh, Luke S., Joubert, Jacques, Garcia-Granda, Santiago, El-Emam, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433897/
https://www.ncbi.nlm.nih.gov/pubmed/34500764
http://dx.doi.org/10.3390/molecules26175335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433897/
https://www.ncbi.nlm.nih.gov/pubmed/34500764
http://dx.doi.org/10.3390/molecules26175335

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