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A Fluorine-19 Magnetic Resonance Probe, Shiga-Y5, Downregulates Thioredoxin-Interacting Protein Expression in the Brain of a Mouse Model of Alzheimer’s Disease

Thioredoxin-interacting protein (TXNIP) is involved in multiple disease-associated functions related to oxidative stress, especially by inhibiting the anti-oxidant- and thiol-reducing activity of thioredoxin (TXN). Shiga-Y5 (SY5), a fluorine-19 magnetic resonance probe for detecting amyloid-β deposi...

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Detalles Bibliográficos
Autores principales: Pahrudin Arrozi, Aslina, Abu Bakar, Zulzikry Hafiz, Taguchi, Hiroyasu, Yanagisawa, Daijiro, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433978/
https://www.ncbi.nlm.nih.gov/pubmed/34500775
http://dx.doi.org/10.3390/molecules26175342