Non-Hydroxamate Zinc-Binding Groups as Warheads for Histone Deacetylases

Histone deacetylases (HDACs) remove acetyl groups from acetylated lysine residues and have a large variety of substrates and interaction partners. Therefore, it is not surprising that HDACs are involved in many diseases. Most inhibitors of zinc-dependent HDACs (HDACis) including approved drugs conta...

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Detalles Bibliográficos
Autores principales: Frühauf, Anton, Meyer-Almes, Franz-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434074/
https://www.ncbi.nlm.nih.gov/pubmed/34500583
http://dx.doi.org/10.3390/molecules26175151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434074/
https://www.ncbi.nlm.nih.gov/pubmed/34500583
http://dx.doi.org/10.3390/molecules26175151

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