Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors

The past few decades have witnessed significant progress in anticancer drug discovery. Small molecules containing heterocyclic moieties have attracted considerable interest for designing new antitumor agents. Of these, the pyrimidine ring system is found in multitude of drug structures, and being th...

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Detalles Bibliográficos
Autores principales: Jadhav, Mrunal, Sankhe, Kaksha, Bhandare, Richie R., Edis, Zehra, Bloukh, Samir Haj, Khan, Tabassum Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434097/
https://www.ncbi.nlm.nih.gov/pubmed/34500603
http://dx.doi.org/10.3390/molecules26175170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434097/
https://www.ncbi.nlm.nih.gov/pubmed/34500603
http://dx.doi.org/10.3390/molecules26175170

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