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Tissue-Specific Regulation of HNK-1 Biosynthesis by Bisecting GlcNAc

Human natural killer—1 (HNK-1) is a sulfated glyco-epitope regulating cell adhesion and synaptic functions. HNK-1 and its non-sulfated forms, which are specifically expressed in the brain and the kidney, respectively, are distinctly biosynthesized by two homologous glycosyltransferases: GlcAT-P in t...

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Detalles Bibliográficos
Autores principales: Kawade, Haruka, Morise, Jyoji, Mishra, Sushil K., Tsujioka, Shuta, Oka, Shogo, Kizuka, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434142/
https://www.ncbi.nlm.nih.gov/pubmed/34500611
http://dx.doi.org/10.3390/molecules26175176