Harnessing the Anti-Nociceptive Potential of NK2 and NK3 Ligands in the Design of New Multifunctional μ/δ-Opioid Agonist–Neurokinin Antagonist Peptidomimetics

Opioid agonists are well-established analgesics, widely prescribed for acute but also chronic pain. However, their efficiency comes with the price of drastically impacting side effects that are inherently linked to their prolonged use. To answer these liabilities, designed multiple ligands (DMLs) of...

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Detalles Bibliográficos
Autores principales: Gadais, Charlène, Piekielna-Ciesielska, Justyna, De Neve, Jolien, Martin, Charlotte, Janecka, Anna, Ballet, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434392/
https://www.ncbi.nlm.nih.gov/pubmed/34500841
http://dx.doi.org/10.3390/molecules26175406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434392/
https://www.ncbi.nlm.nih.gov/pubmed/34500841
http://dx.doi.org/10.3390/molecules26175406

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