Trifluoromethylated Flavonoid-Based Isoxazoles as Antidiabetic and Anti-Obesity Agents: Synthesis, In Vitro α-Amylase Inhibitory Activity, Molecular Docking and Structure–Activity Relationship Analysis

Diabetes mellitus is a major health problem globally. The management of carbohydrate digestion provides an alternative treatment. Flavonoids constitute the largest group of polyphenolic compounds, produced by plants widely consumed as food and/or used for therapeutic purposes. As such, isoxazoles ha...

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Detalles Bibliográficos
Autores principales: Algethami, Faisal K., Saidi, Ilyes, Abdelhamid, Hani Nasser, Elamin, Mohamed R., Abdulkhair, Babiker Y., Chrouda, Amani, Ben Jannet, Hichem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434401/
https://www.ncbi.nlm.nih.gov/pubmed/34500647
http://dx.doi.org/10.3390/molecules26175214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434401/
https://www.ncbi.nlm.nih.gov/pubmed/34500647
http://dx.doi.org/10.3390/molecules26175214

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