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Long-term culture of SH-SY5Y neuroblastoma cells in the absence of neurotrophins: A novel model of neuronal ageing

BACKGROUND: Studying human ageing is of increasing importance due to the worldwide ageing population. However, it faces the challenge of lengthy experiments to produce an ageing phenotype. Often, to recreate the hallmarks of ageing requires complex empirical conditions that can confound data interpr...

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Detalles Bibliográficos
Autores principales: Strother, Lisa, Miles, Gareth B., Holiday, Alison R., Cheng, Ying, Doherty, Gayle H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434422/
https://www.ncbi.nlm.nih.gov/pubmed/34343572
http://dx.doi.org/10.1016/j.jneumeth.2021.109301