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Extrapolating from acute to chronic toxicity in vitro
Chemical safety assessment requires information on both chronic and acute effects of toxicants. Traditionally, such information has been provided by a set of animal studies conducted over different durations, ranging from a single dose with observation of effects over a few days, to repeat daily dos...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434427/ https://www.ncbi.nlm.nih.gov/pubmed/34186185 http://dx.doi.org/10.1016/j.tiv.2021.105206 |