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Quantitative Structure–Activity Relationships of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents

On the basis of the finding that various aminoalkyl-substituted chromene and chromane derivatives possess strong and highly selective in vitro bioactivity against Plasmodium falciparum, the pathogen responsible for tropical malaria, we performed a structure–activity relationship study for such compo...

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Detalles Bibliográficos
Autores principales: Wunsch, Friederike M., Wünsch, Bernhard, Bernal, Freddy A., Schmidt, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434475/
https://www.ncbi.nlm.nih.gov/pubmed/34500683
http://dx.doi.org/10.3390/molecules26175249