Insights into Conformational Dynamics and Allostery in DNMT1-H3Ub/USP7 Interactions

DNA methyltransferases (DNMTs) including DNMT1 are a conserved family of cytosine methylases that play crucial roles in epigenetic regulation. The versatile functions of DNMT1 rely on allosteric networks between its different interacting partners, emerging as novel therapeutic targets. In this work,...

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Detalles Bibliográficos
Autores principales: Zhu, Yu, Ye, Fei, Zhou, Ziyun, Liu, Wanlin, Liang, Zhongjie, Hu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434485/
https://www.ncbi.nlm.nih.gov/pubmed/34500587
http://dx.doi.org/10.3390/molecules26175153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434485/
https://www.ncbi.nlm.nih.gov/pubmed/34500587
http://dx.doi.org/10.3390/molecules26175153

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