Bypassing the Resistance Mechanisms of the Tumor Ecosystem by Targeting the Endoplasmic Reticulum Stress Pathway Using Ruthenium- and Osmium-Based Organometallic Compounds: An Exciting Long-Term Collaboration with Dr. Michel Pfeffer

Metal complexes have been used to treat cancer since the discovery of cisplatin and its interaction with DNA in the 1960’s. Facing the resistance mechanisms against platinum salts and their side effects, safer therapeutic approaches have been sought through other metals, including ruthenium. In the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaiddon, Christian, Gross, Isabelle, Meng, Xiangjun, Sidhoum, Marjorie, Mellitzer, Georg, Romain, Benoit, Delhorme, Jean-Batiste, Venkatasamy, Aïna, Jung, Alain C., Pfeffer, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434532/
https://www.ncbi.nlm.nih.gov/pubmed/34500819
http://dx.doi.org/10.3390/molecules26175386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434532/
https://www.ncbi.nlm.nih.gov/pubmed/34500819
http://dx.doi.org/10.3390/molecules26175386

Ejemplares similares