Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32

Imidazo[1,2-b]pyridazine compounds are a new class of promising lead molecules to which we have incorporated polar nitro and amino moieties to increase the scope of their biological activity. Two of these substituted 3-nitro-6-amino-imidazo[1,2-b]pyridazine compounds (5c and 5h) showed potent acetyl...

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Detalles Bibliográficos
Autores principales: Sharma, Rakesh Kumar, Singh, Manisha, Ghimeray, Khagendra, Juneja, Pinky, Dev, Gagan, Pulavarthi, Sridhar, Reddy, Sabbasani Rajasekhara, Akundi, Ravi Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434581/
https://www.ncbi.nlm.nih.gov/pubmed/34500749
http://dx.doi.org/10.3390/molecules26175319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434581/
https://www.ncbi.nlm.nih.gov/pubmed/34500749
http://dx.doi.org/10.3390/molecules26175319

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