Phosphate-Based Self-Immolative Linkers for the Delivery of Amine-Containing Drugs

Amine-containing drugs often show poor pharmacological properties, but these disadvantages can be overcome by using a prodrug approach involving self-immolative linkers. Accordingly, we designed l-lactate linkers as ideal candidates for amine delivery. Furthermore, we designed linkers bearing two di...

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Detalles Bibliográficos
Autores principales: Đud, Mateja, Tichotová, Markéta, Procházková, Eliška, Baszczyňski, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434617/
https://www.ncbi.nlm.nih.gov/pubmed/34500595
http://dx.doi.org/10.3390/molecules26175160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434617/
https://www.ncbi.nlm.nih.gov/pubmed/34500595
http://dx.doi.org/10.3390/molecules26175160

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