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Phosphate-Based Self-Immolative Linkers for the Delivery of Amine-Containing Drugs
Amine-containing drugs often show poor pharmacological properties, but these disadvantages can be overcome by using a prodrug approach involving self-immolative linkers. Accordingly, we designed l-lactate linkers as ideal candidates for amine delivery. Furthermore, we designed linkers bearing two di...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434617/ https://www.ncbi.nlm.nih.gov/pubmed/34500595 http://dx.doi.org/10.3390/molecules26175160 |