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Knockdown of PGM1 enhances anticancer effects of orlistat in gastric cancer under glucose deprivation

BACKGROUND: Phosphoglucomutase 1 (PGM1) acts as an important regulator in glucose metabolism. However, the role of PGM1 in gastric cancer (GC) remains unclear. This study aims to investigate the role of PGM1 and develop novel regimens based on metabolic reprogramming in GC. METHODS: Correlation and...

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Detalles Bibliográficos
Autores principales: Cao, Bo, Deng, Huan, Cui, Hao, Zhao, Ruiyang, Li, Hanghang, Wei, Bo, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434706/
https://www.ncbi.nlm.nih.gov/pubmed/34507580
http://dx.doi.org/10.1186/s12935-021-02193-3