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Mitochondrial Targeting of the Ammonia-Sensitive Uncoupler SLC4A11 by the Chaperone-Mediated Carrier Pathway in Corneal Endothelium

PURPOSE: SLC4A11, an electrogenic H(+) transporter, is found in the plasma membrane and mitochondria of corneal endothelium. However, the underlying mechanism of SLC4A11 targeting to mitochondria is unknown. METHODS: The presence of mitochondrial targeting sequences was examined using in silico mito...

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Detalles Bibliográficos
Autores principales: Choi, Moonjung, Bonanno, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434753/
https://www.ncbi.nlm.nih.gov/pubmed/34499705
http://dx.doi.org/10.1167/iovs.62.12.4