Using CRISPR Interference as a Therapeutic Approach to Treat TGFβ2-Induced Ocular Hypertension and Glaucoma

PURPOSE: Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide with elevated intraocular pressure (IOP) as the most important risk factor. POAG IOP elevation is due to pathological changes in the trabecular meshwork (TM). Elevated TGFβ2 contributes to these changes and increas...

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Detalles Bibliográficos
Autores principales: Rayana, Naga Pradeep, Sugali, Chenna Kesavulu, Dai, Jiannong, Peng, Michael, Liu, Shaohui, Zhang, Yucheng, Wan, Jun, Mao, Weiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434756/
https://www.ncbi.nlm.nih.gov/pubmed/34499703
http://dx.doi.org/10.1167/iovs.62.12.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434756/
https://www.ncbi.nlm.nih.gov/pubmed/34499703
http://dx.doi.org/10.1167/iovs.62.12.7

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