Oxidative Stress Resistance 1 Gene Therapy Retards Neurodegeneration in the rd1 Mutant Mouse Model of Retinopathy

PURPOSE: Oxidative stress is a major factor underlying many neurodegenerative diseases. However, antioxidant therapy has had mixed results, possibly because of its indiscriminate activity. The purpose of our study was to determine if the human OXR1 (hOXR1) antioxidant regulatory gene could protect n...

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Detalles Bibliográficos
Autores principales: Sahu, Bhubanananda, Leon, Laura Moreno, Zhang, Wei, Puranik, Nikita, Periasamy, Ramesh, Khanna, Hemant, Volkert, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434758/
https://www.ncbi.nlm.nih.gov/pubmed/34505865
http://dx.doi.org/10.1167/iovs.62.12.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434758/
https://www.ncbi.nlm.nih.gov/pubmed/34505865
http://dx.doi.org/10.1167/iovs.62.12.8

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