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EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2

WNT signalling is important for development in all metazoans and is associated with various human diseases. The ubiquitin–proteasome system (UPS) and regulatory endoplasmic reticulum-associated degradation (ERAD) have been implicated in the production of WNT proteins. Here, we investigated how the W...

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Detalles Bibliográficos
Autores principales: Wolf, Lucie M., Lambert, Annika M., Haenlin, Julie, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435288/
https://www.ncbi.nlm.nih.gov/pubmed/34406391
http://dx.doi.org/10.1242/jcs.257790