The stressosome, a caspase‐8‐activating signalling complex assembled in response to cell stress in an ATG5‐mediated manner

Stress‐induced apoptosis is mediated primarily through the intrinsic pathway that involves caspase‐9. We previously reported that in caspase‐9‐deficient cells, a protein complex containing ATG5 and Fas‐associated death domain (FADD) facilitated caspase‐8 activation and cell death in response to endo...

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Detalles Bibliográficos
Autores principales: Mnich, Katarzyna, Koryga, Izabela, Pakos‐Zebrucka, Karolina, Thomas, Melissa, Logue, Susan E., Eriksson, Leif A., Gorman, Adrienne M., Samali, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435408/
https://www.ncbi.nlm.nih.gov/pubmed/34363313
http://dx.doi.org/10.1111/jcmm.16840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435408/
https://www.ncbi.nlm.nih.gov/pubmed/34363313
http://dx.doi.org/10.1111/jcmm.16840

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