Cargando…
The stressosome, a caspase‐8‐activating signalling complex assembled in response to cell stress in an ATG5‐mediated manner
Stress‐induced apoptosis is mediated primarily through the intrinsic pathway that involves caspase‐9. We previously reported that in caspase‐9‐deficient cells, a protein complex containing ATG5 and Fas‐associated death domain (FADD) facilitated caspase‐8 activation and cell death in response to endo...
Autores principales: | Mnich, Katarzyna, Koryga, Izabela, Pakos‐Zebrucka, Karolina, Thomas, Melissa, Logue, Susan E., Eriksson, Leif A., Gorman, Adrienne M., Samali, Afshin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435408/ https://www.ncbi.nlm.nih.gov/pubmed/34363313 http://dx.doi.org/10.1111/jcmm.16840 |
Ejemplares similares
-
Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival
por: Saveljeva, Svetlana, et al.
Publicado: (2016) -
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions
por: Deegan, Shane, et al.
Publicado: (2014) -
Structural insights into stressosome assembly
por: Kwon, Eunju, et al.
Publicado: (2019) -
An Emerging Role for the Unfolded Protein Response in Pancreatic Cancer
por: Robinson, Claire M., et al.
Publicado: (2021) -
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
por: Mnich, K, et al.
Publicado: (2014)