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Pirfenidone modulates macrophage polarization and ameliorates radiation‐induced lung fibrosis by inhibiting the TGF‐β1/Smad3 pathway

Radiation‐induced lung injury (RILI) mainly contributes to the complications of thoracic radiotherapy. RILI can be divided into radiation pneumonia (RP) and radiation‐induced lung fibrosis (RILF). Once RILF occurs, patients will eventually develop irreversible respiratory failure; thus, a new treatm...

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Detalles Bibliográficos
Autores principales: Ying, Hangjie, Fang, Min, Hang, Qing Qing, Chen, Yamei, Qian, Xu, Chen, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435416/
https://www.ncbi.nlm.nih.gov/pubmed/34327818
http://dx.doi.org/10.1111/jcmm.16821