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Recapitulative haematopoietic development of human pluripotent stem cells in the absence of exogenous haematopoietic cytokines

To improve the recapitulative quality of human pluripotent stem cell (hPSC) differentiation, we removed exogenous haematopoietic cytokines from the defined differentiation system. Here, we show that endogenous stimuli and VEGF are sufficient to induce robust hPSC‐derived haematopoiesis, intensive ge...

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Detalles Bibliográficos
Autores principales: Philonenko, Elena S., Tan, Ying, Wang, Cuihua, Zhang, Baoyun, Shah, Zahir, Zhang, Jianguang, Ullah, Hanif, Kiselev, Sergei L., Lagarkova, Maria A., Li, Dandan, Dai, Yong, Samokhvalov, Igor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435420/
https://www.ncbi.nlm.nih.gov/pubmed/34342123
http://dx.doi.org/10.1111/jcmm.16826