Cargando…
Recapitulative haematopoietic development of human pluripotent stem cells in the absence of exogenous haematopoietic cytokines
To improve the recapitulative quality of human pluripotent stem cell (hPSC) differentiation, we removed exogenous haematopoietic cytokines from the defined differentiation system. Here, we show that endogenous stimuli and VEGF are sufficient to induce robust hPSC‐derived haematopoiesis, intensive ge...
Autores principales: | Philonenko, Elena S., Tan, Ying, Wang, Cuihua, Zhang, Baoyun, Shah, Zahir, Zhang, Jianguang, Ullah, Hanif, Kiselev, Sergei L., Lagarkova, Maria A., Li, Dandan, Dai, Yong, Samokhvalov, Igor M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435420/ https://www.ncbi.nlm.nih.gov/pubmed/34342123 http://dx.doi.org/10.1111/jcmm.16826 |
Ejemplares similares
-
MYB bi-allelic targeting abrogates primitive clonogenic progenitors while the emergence of primitive blood cells is not affected
por: Shah, Zahir, et al.
Publicado: (2020) -
Why are haematopoietic stem cells in the bone marrow: ontology recapitulates phylogeny
por: Gale, Robert Peter, et al.
Publicado: (2023) -
Haematopoietic development and immunological function in the absence of cathepsin D
por: Tulone, Calogero, et al.
Publicado: (2007) -
Haematopoietic stem and progenitor cells from human pluripotent stem cells
por: Sugimura, Ryohichi, et al.
Publicado: (2017) -
Regulation of haematopoietic multipotency by EZH1
por: Vo, Linda T., et al.
Publicado: (2018)