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Targeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancer

Colorectal cancer (CRC) is the third most malignant tumour worldwide, with high mortality and recurrence. Chemoresistance is one of the main factors leading to metastasis and poor prognosis in advanced CRC patients. By analysing the Gene Expression Omnibus data set, we found higher hexokinase 2 (HK2...

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Chan, Sze‐Hoi, Liu, Xue‐Qi, Shi, Yuan‐Yuan, Dong, Zhao‐Xia, Shao, Xin‐Rong, Zheng, Li‐Yuan, Mai, Zhi‐Ying, Fang, Tian‐Liang, Deng, Li‐Zhi, Zhou, Di‐Sheng, Chen, Shu‐Na, Li, Miao, Zhang, Xing‐Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435428/
https://www.ncbi.nlm.nih.gov/pubmed/34378321
http://dx.doi.org/10.1111/jcmm.16842