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Biodistribution of adeno‐associated virus type 2 carrying multi‐characteristic opsin in dogs following intravitreal injection

Gene therapy of retinal diseases using recombinant adeno‐associated virus (rAAV) vector‐based delivery has shown clinical success, and clinical trials based on rAAV‐based optogenetic therapies are currently in progress. Recently, we have developed multi‐characteristic opsin (MCO), which has been sho...

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Detalles Bibliográficos
Autores principales: Tchedre, Kissaou T., Batabyal, Subrata, Galicia, Melissa, Narcisse, Darryl, Mustafi, Sourajit Mitra, Ayyagari, Ananta, Chavala, Sai, Mohanty, Samarendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435460/
https://www.ncbi.nlm.nih.gov/pubmed/34418301
http://dx.doi.org/10.1111/jcmm.16823