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EMP3 negatively modulates breast cancer cell DNA replication, DNA damage repair, and stem-like properties
Enhanced DNA damage repair capacity attenuates cell killing of DNA-damaging chemotherapeutic agents. In silico analysis showed that epithelial membrane protein 3 (EMP3) is associated with favorable survival, and negatively regulates cell cycle S-phase. Consistently, loss and gain of function studies...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435533/ https://www.ncbi.nlm.nih.gov/pubmed/34511602 http://dx.doi.org/10.1038/s41419-021-04140-6 |