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EMP3 negatively modulates breast cancer cell DNA replication, DNA damage repair, and stem-like properties

Enhanced DNA damage repair capacity attenuates cell killing of DNA-damaging chemotherapeutic agents. In silico analysis showed that epithelial membrane protein 3 (EMP3) is associated with favorable survival, and negatively regulates cell cycle S-phase. Consistently, loss and gain of function studies...

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Detalles Bibliográficos
Autores principales: Zhou, Kailing, Sun, Yu, Dong, Dan, Zhao, Chenghai, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435533/
https://www.ncbi.nlm.nih.gov/pubmed/34511602
http://dx.doi.org/10.1038/s41419-021-04140-6