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Mechanism of Paeoniflorin on ANIT-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology

Background: Paeoniflorin (PF), the major active compound isolated from the roots of Paeonia lactiflora Pall., has been used in the treatment of severe hepatic diseases for several decades and displays bright prospects in liver protective effect. However, its biological mechanism that regulates bile...

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Detalles Bibliográficos
Autores principales: Chen, Lisheng, Zhao, Xu, Wei, Shizhang, Ma, Xiao, Liu, Honghong, Li, Jianyu, Jing, Manyi, Wang, Min, Zhao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435635/
https://www.ncbi.nlm.nih.gov/pubmed/34526905
http://dx.doi.org/10.3389/fphar.2021.737630