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Propranolol Inhibits the Proliferation of Human Glioblastoma Cell Lines through Notch1 and Hes1 Signaling System

OBJECTIVE: The anti-tumor effect of the beta-adrenergic receptor antagonist propranolol in breast cancer is well known; however, its activity in glioblastoma is not well-evaluated. The Notch-Hes pathway is known to regulate cell differentiation, proliferation, and apoptosis. We investigated the effe...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Sik, Park, Young Han, Lee, Heui Seung, Kwon, Mi Jung, Song, Joon Ho, Chang, In Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435645/
https://www.ncbi.nlm.nih.gov/pubmed/34376038
http://dx.doi.org/10.3340/jkns.2021.0068