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Optimal Ratio of Wnt3a Expression in Human Mesenchymal Stem Cells Promotes Axonal Regeneration in Spinal Cord Injured Rat Model

OBJECTIVE: Through our previous clinical trials, the demonstrated therapeutic effects of MSC in chronic spinal cord injury (SCI) were found to be not sufficient. Therefore, the need to develop stem cell agent with enhanced efficacy is increased. We transplanted enhanced Wnt3a-secreting human mesench...

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Detalles Bibliográficos
Autores principales: Yoon, Hyung Ho, Lee, Hyang Ju, Min, Joongkee, Kim, Jeong Hoon, Park, Jin Hoon, Kim, Ji Hyun, Kim, Seong Who, Lee, Heuiran, Jeon, Sang Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435649/
https://www.ncbi.nlm.nih.gov/pubmed/34044494
http://dx.doi.org/10.3340/jkns.2021.0003