Integration of T helper and BCR signals governs enhanced plasma cell differentiation of memory B cells by regulation of CD45 phosphatase activity

Humoral immunity relies on the efficient differentiation of memory B cells (MBCs) into antibody-secreting cells (ASCs). T helper (Th) signals upregulate B cell receptor (BCR) signaling by potentiating Src family kinases through increasing CD45 phosphatase activity (CD45 PA). In this study, we show t...

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Detalles Bibliográficos
Autores principales: Szodoray, Peter, Andersen, Tor Kristian, Heinzelbecker, Julia, Imbery, John F., Huszthy, Peter C., Stanford, Stephanie M., Bogen, Bjarne, Landsverk, Ole B., Bottini, Nunzio, Tveita, Anders, Munthe, Ludvig A., Nakken, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435664/
https://www.ncbi.nlm.nih.gov/pubmed/34380042
http://dx.doi.org/10.1016/j.celrep.2021.109525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435664/
https://www.ncbi.nlm.nih.gov/pubmed/34380042
http://dx.doi.org/10.1016/j.celrep.2021.109525

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