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Cardioprotecive Properties of Known Agents in Rat Ischemia-Reperfusion Model Under Clinically Relevant Conditions: Only the NAD Precursor Nicotinamide Riboside Reduces Infarct Size in Presence of Fentanyl, Midazolam and Cangrelor, but Not Propofol

Background: Cardioprotective strategies against ischemia-reperfusion injury (IRI) that remain effective in the clinical arena need to be developed. Therefore, maintained efficacy of cardioprotective strategies in the presence of drugs routinely used clinically (e.g., opiates, benzodiazepines, P2Y(12...

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Detalles Bibliográficos
Autores principales: Xiao, Yang, Phelp, Philippa, Wang, Qian, Bakker, Diane, Nederlof, Rianne, Hollmann, Markus W., Zuurbier, Coert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435675/
https://www.ncbi.nlm.nih.gov/pubmed/34527711
http://dx.doi.org/10.3389/fcvm.2021.712478