Creation of an Anti-Inflammatory, Leptin-Dependent Anti-Obesity Celastrol Mimic with Better Druggability

Obesity is characterized by an excessive body mass, but is also closely associated with metabolic syndrome. And, so far, only limited pharmacological treatments are available for obesity management. Celastrol, a pentacyclic triterpenoid from a traditional Chinese medicine (Tripterygium wilfordii Hoo...

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Detalles Bibliográficos
Autores principales: Zhou, Bo, Yuan, Yaxia, Shi, Le, Hu, Sheng, Wang, Dong, Yang, Yang, Pan, Yuanhu, Kong, Dexin, Shikov, Alexander N., Duez, Pierre, Jin, Moonsoo, Li, Xiaohua, Hu, Xuebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435713/
https://www.ncbi.nlm.nih.gov/pubmed/34526895
http://dx.doi.org/10.3389/fphar.2021.705252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435713/
https://www.ncbi.nlm.nih.gov/pubmed/34526895
http://dx.doi.org/10.3389/fphar.2021.705252

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