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Creation of an Anti-Inflammatory, Leptin-Dependent Anti-Obesity Celastrol Mimic with Better Druggability
Obesity is characterized by an excessive body mass, but is also closely associated with metabolic syndrome. And, so far, only limited pharmacological treatments are available for obesity management. Celastrol, a pentacyclic triterpenoid from a traditional Chinese medicine (Tripterygium wilfordii Hoo...
Autores principales: | Zhou, Bo, Yuan, Yaxia, Shi, Le, Hu, Sheng, Wang, Dong, Yang, Yang, Pan, Yuanhu, Kong, Dexin, Shikov, Alexander N., Duez, Pierre, Jin, Moonsoo, Li, Xiaohua, Hu, Xuebo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435713/ https://www.ncbi.nlm.nih.gov/pubmed/34526895 http://dx.doi.org/10.3389/fphar.2021.705252 |
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