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Host Serine Proteases: A Potential Targeted Therapy for COVID-19 and Influenza

The ongoing pandemic illustrates limited therapeutic options for controlling SARS-CoV-2 infections, calling a need for additional therapeutic targets. The viral spike S glycoprotein binds to the human receptor angiotensin-converting enzyme 2 (ACE2) and then is activated by the host proteases. Based...

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Detalles Bibliográficos
Autores principales: Rahbar Saadat, Yalda, Hosseiniyan Khatibi, Seyed Mahdi, Zununi Vahed, Sepideh, Ardalan, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435734/
https://www.ncbi.nlm.nih.gov/pubmed/34527703
http://dx.doi.org/10.3389/fmolb.2021.725528