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Transcriptome Signature of Vγ9Vδ2 T Cells Treated With Phosphoantigens and Notch Inhibitor Reveals Interplay Between TCR and Notch Signaling Pathways

Gamma delta (γδ) T cells, especially the Vγ9Vδ2 subtype, have been implicated in cancer therapy and thus have earned the spotlight in the past decade. Although one of the most important properties of γδ T cells is their activation by phosphoantigens, which are intermediates of the Mevalonate and Roh...

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Detalles Bibliográficos
Autores principales: Madhok, Ayush, Bhat, Sajad Ahmad, Philip, Chinna Susan, Sureshbabu, Shalini Kashipathi, Chiplunkar, Shubhada, Galande, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435775/
https://www.ncbi.nlm.nih.gov/pubmed/34526984
http://dx.doi.org/10.3389/fimmu.2021.660361