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Transcriptome Signature of Vγ9Vδ2 T Cells Treated With Phosphoantigens and Notch Inhibitor Reveals Interplay Between TCR and Notch Signaling Pathways
Gamma delta (γδ) T cells, especially the Vγ9Vδ2 subtype, have been implicated in cancer therapy and thus have earned the spotlight in the past decade. Although one of the most important properties of γδ T cells is their activation by phosphoantigens, which are intermediates of the Mevalonate and Roh...
Autores principales: | Madhok, Ayush, Bhat, Sajad Ahmad, Philip, Chinna Susan, Sureshbabu, Shalini Kashipathi, Chiplunkar, Shubhada, Galande, Sanjeev |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435775/ https://www.ncbi.nlm.nih.gov/pubmed/34526984 http://dx.doi.org/10.3389/fimmu.2021.660361 |
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