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Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury

Rationale: Galectin-3 (Gal-3) is an immune regulator and an important driver of fibrosis in chronic lung injury, however, its role in acute lung injury (ALI) remains unknown. Previous work has shown that global deletion of galectin-3 reduces collagen deposition in a bleomycin-induced pulmonary fibro...

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Detalles Bibliográficos
Autores principales: Humphries, Duncan C., Mills, Ross, Dobie, Ross, Henderson, Neil C., Sethi, Tariq, Mackinnon, Alison C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435800/
https://www.ncbi.nlm.nih.gov/pubmed/34526900
http://dx.doi.org/10.3389/fphar.2021.715986