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Molecular phenotypes reveal heterogeneous engraftments of patient-derived hepatocellular carcinoma xenografts

OBJECTIVE: Patient-derived xenograft (PDX) models provide a promising preclinical platform for hepatocellular carcinoma (HCC). However, the molecular features associated with successful engraftment of PDX models have not been revealed. METHODS: HCC tumor samples from 76 patients were implanted in im...

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Detalles Bibliográficos
Autores principales: Zhuo, Jianyong, Lu, Di, Wang, Jianguo, Lian, Zhengxing, Zhang, Jiali, Li, Huihui, Cen, Beini, Wei, Xuyong, Wei, Qiang, Xie, Haiyang, Xu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435819/
https://www.ncbi.nlm.nih.gov/pubmed/34584372
http://dx.doi.org/10.21147/j.issn.1000-9604.2021.04.04