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Berberine Acts on C/EBPβ/lncRNA Gas5/miR-18a-5p Loop to Decrease the Mitochondrial ROS Generation in HK-2 Cells

BACKGROUND: Berberine (BBR) has therapeutic effect on diabetic nephropathy (DN), but its molecular mechanism is not completely clear. METHODS: The DN model was established to observe the therapeutic effect of BBR. The expression levels of lncRNA Gas5 were detected by PCR. The transcriptional regulat...

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Detalles Bibliográficos
Autores principales: Xu, Jiang, Liu, Linqing, Gan, Lin, Hu, Yuanyuan, Xiang, Ping, Xing, Yan, Zhu, Jie, Ye, Shandong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435884/
https://www.ncbi.nlm.nih.gov/pubmed/34526965
http://dx.doi.org/10.3389/fendo.2021.675834