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The effect of α-tocopherol, α- and γ-tocotrienols on amyloid-β aggregation and disaggregation in vitro

One of the neuropathological hallmarks of Alzheimer's disease (AD)—causing neurodegeneration and consequent memory deterioration, and eventually, cognitive decline—is amyloid-β (Aβ) aggregation forming amyloid plaques. Our previous study showed the potential of a tocotrienol-rich fraction—a mix...

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Detalles Bibliográficos
Autores principales: Ibrahim, Nor Faeizah, Hamezah, Hamizah Shahirah, Yanagisawa, Daijiro, Tsuji, Mayumi, Kiuchi, Yuji, Ono, Kenjiro, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435913/
https://www.ncbi.nlm.nih.gov/pubmed/34541343
http://dx.doi.org/10.1016/j.bbrep.2021.101131