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Simultaneous silencing Aurora-A and UHRF1 inhibits colorectal cancer cell growth through regulating expression of DNMT1 and STAT1

Aurora-A has attracted a great deal of interest as a potential therapeutic target for patients with CRC. However, the outcomes of inhibitors targeting Aurora-A are not as favorable as expected, and the basis behind the ineffectiveness remains unknown. Here, we found that signal transducer and activa...

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Detalles Bibliográficos
Autores principales: Han, Jing, Chen, Xin, Xu, Jiawei, Chu, Laili, Li, Rongqing, Sun, Na, Jiang, Zhen, Liu, Hongyang, Ge, Xing, Zheng, Junnian, Yang, Jing, Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436113/
https://www.ncbi.nlm.nih.gov/pubmed/34522170
http://dx.doi.org/10.7150/ijms.61969