Cargando…

Targeting Notch4 in Cancer: Molecular Mechanisms and Therapeutic Perspectives

The dysregulation of Notch signaling is found in many cancers and is closely related to cancer progression. As an important Notch receptor, abnormal Notch4 expression affects several tumor-cell behaviors, including stemness, the epithelial–mesenchymal transition, radio/chemoresistance and angiogenes...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiu, Mengxi, Zeng, Xiaohong, Shan, Renfeng, Wen, Wu, Li, Jianfeng, Wan, Renhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436177/
https://www.ncbi.nlm.nih.gov/pubmed/34526819
http://dx.doi.org/10.2147/CMAR.S315511