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Lycium barbarum polysaccharide protects rats and cardiomyocytes against ischemia/reperfusion injury via Nrf2 activation through autophagy inhibition

The irreversible loss of cardiomyocytes is mainly the result of ischemic/reperfusion (I/R) myocardial injury, leading to persistent heart dysfunction and heart failure. It has been reported that Lycium barbarum polysaccharide (LBP) has protective effects on cardiomyocytes, but the specific mechanism...

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Detalles Bibliográficos
Autores principales: Pan, Hao, Niu, Lin, Wu, Yihao, Chen, Liuying, Zhou, Xiaowei, Zhao, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436221/
https://www.ncbi.nlm.nih.gov/pubmed/34498711
http://dx.doi.org/10.3892/mmr.2021.12418