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miR221 regulates TGF-β1-induced HSC activation through inhibiting autophagy by directly targeting LAMP2

Liver fibrosis is a serious threat to human life and health. Activated hepatic stellate cells (HSCs) play a key role in the occurrence and development of liver fibrosis. Studies have reported that microRNAs (miRNAs/miRs) are involved in the pathological process of fibrosis, as well as its relevance...

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Detalles Bibliográficos
Autores principales: Cheng, Ran, Xu, Hao, Hong, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436230/
https://www.ncbi.nlm.nih.gov/pubmed/34498712
http://dx.doi.org/10.3892/mmr.2021.12417