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Structural Insights into the Mechanisms and Pharmacology of K(2P) Potassium Channels

Leak currents, defined as voltage and time independent flows of ions across cell membranes, are central to cellular electrical excitability control. The K(2P) (KCNK) potassium channel class comprises an ion channel family that produces potassium leak currents that oppose excitation and stabilize the...

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Detalles Bibliográficos
Autores principales: Natale, Andrew M., Deal, Parker E., Minor, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436263/
https://www.ncbi.nlm.nih.gov/pubmed/33887333
http://dx.doi.org/10.1016/j.jmb.2021.166995