Improving the Adjuvanticity of Small Molecule Immune Potentiators Using Covalently Linked NF-κB Modulators

[Image: see text] Small molecule immune potentiators (SMIPs) such as imidazoquinolinone derivatives that activate Toll-like receptor (TLR) 7/8 have immense potential as vaccine adjuvants and as antitumor agents. However, these molecules have high bioavailability that results in unacceptable levels o...

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Detalles Bibliográficos
Autores principales: Kimani, Flora W., Manna, Saikat, Moser, Brittany, Shen, Jingjing, Nihesh, Naorem, Esser-Kahn, Aaron P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436408/
https://www.ncbi.nlm.nih.gov/pubmed/34527180
http://dx.doi.org/10.1021/acsmedchemlett.1c00267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436408/
https://www.ncbi.nlm.nih.gov/pubmed/34527180
http://dx.doi.org/10.1021/acsmedchemlett.1c00267

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