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Kynurenine pathway in post-mortem prefrontal cortex and cerebellum in schizophrenia: relationship with monoamines and symptomatology

BACKGROUND: The cortico-cerebellar-thalamic-cortical circuit has been implicated in the emergence of psychotic symptoms in schizophrenia (SZ). The kynurenine pathway (KP) has been linked to alterations in glutamatergic and monoaminergic neurotransmission and to SZ symptomatology through the producti...

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Detalles Bibliográficos
Autores principales: Afia, Amira Ben, Vila, Èlia, MacDowell, Karina S., Ormazabal, Aida, Leza, Juan C., Haro, Josep M., Artuch, Rafael, Ramos, Belén, Garcia-Bueno, Borja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436477/
https://www.ncbi.nlm.nih.gov/pubmed/34511126
http://dx.doi.org/10.1186/s12974-021-02260-6